The Parkinson's disease and has been a very research tigada by scientists and medical products and very negative effects on the patients TES qu and prevent them to accomplish His s normal daily activities d, besides is not precisely in and a rarity in developed countries.
brain activity With Parkinson's and neurological diseases in general has long been problems and confusion in their treatment, due to the difficulty of acting on the nervous tissue but in recent decades with the development of genetics and its application to medicine are making great advanced ces in the treatment of this and other types of patients ages.
in the U.S. has succeeded in improving the status of several patients suffering from Parkinson's disease by gene therapy known as NLX-P101.
this therapy was achieved by examining the effect of the introduction of the gene for the enzyme glutamic acid decarboxylase (GAD) in the subthalamic nucleus of patients, compared with resp after et up to surgery.
Scheme taken from the ABC represents the process of therapy. therapy was the introduction of the GAD gene via a vector (a virus carrying the gene) which transfers it to the DNA of neurons, which causes it to produce the enzyme which releases a neurotransmitter ( GABA) exists in a very small number of patients whose deficit is causing the lack of control of voluntary movements, rigidity and tremor.
The treatment has been a marked improvement in 22 patients and as an enhancement of the tremor, gait, movements, and posture and the ability to make more fluid movements and a reduction freezing periods in which some patients are unable to move.
This therapy has produced great results for patients but it remains unclear how long the effects remain positive and if need be carried out regularly this therapy in patients to maintain genes.
Sources:
World
ABC
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